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UK SPECIALISTS IN GENDER THERAPY

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Dr Leighton J Seal

PhD FRCP
Consultant Endocrinologist and Senior Gender Specialist
GMC no. 3663491

Dr Leighton J Seal
Professor Seal trained at St Bartholomew's hospital London qualifying in 1992. He gained several prizes during his undergraduate career and he was awarded the Betuel Prize for Medicine by the University of London when he graduated.
His post graduate training and research was at the Royal postgraduate medical School Hammersmith Hospital and Imperial College London. He was awarded a Wellcome Trust Clinical Training Fellowship and his research interest was in the hypothalamic control of reproduction. He was awarded a PhD in 2003 and has published over 30 papers in peer-reviewed journals.

Professor Seal joined St George's University hospitals NHS foundation trust in 2003. He is a Consultant and Professor in Endocrinology and Diabetes. His clinical interests are in pituitary disease, adrenal disease and he specialises in medical andrology. He leads the andrology services in the department of endocrinology.

Since 2003 he has also been the Consultant Endocrinologist in the Charing Cross Adult Gender Identity Clinic which moved to the Tavistock and Portman Hospital in 2020. This is the oldest and largest gender identity service in the UK and has been operational since 1966. He developed the endocrine service in this clinic and he has led the development and expansion of the endocrine provision. He is the clinical lead for endocrine services. He is recognised as a gender specialist by the gender recognition panel. In the private sector he works as part of the Gender Care group of gender specialists providing high quality endocrine care to gender nonconforming people.

He is recognised as a national expert in this field.

My research interest is in the role endocrine abnormalities play in the development of disorders of gender identity.

Professional Memberships:
GMC Specialist Register (Diabetes, Endocrinology & General Internal Medicine)
Fellow of the Royal College of Physicians
Member of the Society for Endocrinology
Member of the World Professional Association of Transgender Health
Member of the British Association of Gender Identity Specialists
Royal College of Physicians professional certificate in core capabilities in the clinical practice for adult gender identity healthcare
Physicians professional certificate in clinical practice of gender identity healthcare professional certificate in prescribing capabilities

Publications:

Colwill M, Pollock, R, Seal, L, Poulllis, A  Impact of gender identity in the inflammatory bowel disease population: An evidence review and practical steps gastroenterologists 2024 front line gastroenterology 15 (401–407).

Dimakopoulou, A., & Seal, L. J. (2024). Testosterone and other treatments for transgender males and non-binary trans masculine individuals. Best Pract Res Clin Endocrinol Metab, 38(5), 101908. https://doi.org/10.1016/j.beem.2024.101908

Jayasena, C. N., Devine, K., Barber, K., Comninos, A. N., Conway, G. S., Crown, A.,…Quinton, R. (2024). Society for endocrinology guideline for understanding, diagnosing and treating female hypogonadism. Clin Endocrinol (Oxf), 101(5), 409-442. https://doi.org/10.1111/cen.15097

BERNER, A. M., BUCHANAN, D., SEAL, L. & O'CALLAGHAN, S. 2024. Methodological considerations in the use of a large database to estimate incidence of prostate cancer in transgender women in the US. Prostate Cancer Prostatic Dis.
DIMAKOPOULOU, A. & SEAL, L. J. 2024. Testosterone and other treatments for transgender males and non-binary trans masculine individuals. Best Pract Res Clin Endocrinol Metab, 38, 101908.
JAYASENA, C. N., DEVINE, K., BARBER, K., COMNINOS, A. N., CONWAY, G. S., CROWN, A., DAVIES, M. C., EWART, A., SEAL, L. J., SMYTH, A., TURNER, H. E., WEBBER, L., ANDERSON, R. A. & QUINTON, R. 2024. Society for endocrinology guideline for understanding, diagnosing and treating female hypogonadism. Clin Endocrinol (Oxf), 101, 409-442.
E. Coleman, A. E. Radix, W. P. Bouman, G. R. Brown, A. L. C. de Vries, M. B. Deutsch, R. Ettner, L. Fraser, M. Goodman, J. Green, A. B. Hancock, T. W. Johnson, D. H. Karasic, G. A. Knudson, S. F. Leibowitz, H. F. L. Meyer-Bahlburg, S. J. Monstrey, J. Motmans, L. Nahata, T. O. Nieder, S. L. Reisner, C. Richards, L. S. Schechter, V. Tangpricha, A. C. Tishelman, M. A. A. Van Trotsenburg, S. Winter, K. Ducheny, N. J. Adams, T. M. Adrián, L. R. Allen, D. Azul, H. Bagga, K. Başar, D. S. Bathory, J. J. Belinky, D. R. Berg, J. U. Berli, R. O. Bluebond- Langner, M.-B. Bouman, M. L. Bowers, P. J. Brassard, J. Byrne, L. Capitán, C. J. Cargill, J. M. Carswell, S. C. Chang, G. Chelvakumar, T. Corneil, K. B. Dalke, G. De Cuypere, E. de Vries, M. Den Heijer, A. H. Devor, C. Dhejne, A. D'Marco, E. K. Edmiston, L. Edwards-Leeper, R. Ehrbar, D. Ehrensaft, J. Eisfeld, E. Elaut, L. Erickson-Schroth, J. L. Feldman, A. D. Fisher, M. M. Garcia, L. Gijs, S. E. Green, B. P. Hall, T. L. D. Hardy, M. S. Irwig, L. A. Jacobs, A. C. Janssen, K. Johnson, D. T. Klink, B. P. C. Kreukels, L. E. Kuper, E. J. Kvach, M. A. Malouf, R. Massey, T. Mazur, C. McLachlan, S. D. Morrison, S. W. Mosser, P. M. Neira, U. Nygren, J. M. Oates, J. Obedin-Maliver, G. Pagkalos, J. Patton, N. Phanuphak, K. Rachlin, T. Reed, G. N. Rider, J. Ristori, S. Robbins-Cherry, S. A. Roberts, K. A. Rodriguez-Wallberg, S. M. Rosenthal, K. Sabir, J. D. Safer, A. I. Scheim, L. J. Seal, T. J. Sehoole, K. Spencer, C. St. Amand, T. D. Steensma, J. F. Strang, G. B. Taylor, K. Tilleman, G. G. T'Sjoen, L. N. Vala, N. M. Van Mello, J. F. Veale, J. A. Vencill, B. Vincent, L. M. Wesp, M. A. West & J. Arcelus Standards of Care for the Health of Transgenderand Gender Diverse People, Version 8Int J Transgender Health 2022, VOL. 23, NO. S1, S1–S258 https://doi.org/10.1080/26895269.2022.2100644
Gezer E, Zeynep Canturk BP, Cetinarslan B, Sozen M, Selek A, Iskik AP, L.J. Seal. The comparison of Gender Dysphoria, body image satisfaction and quality of life between treatment naïve transgender male with and without polycystic ovarian syndrome. Transgender Health.2021.
Hamilton BR; Guppy FM; Barrett J; Seal L; Pitsiladis Y. Integrating transwomen athletes into elite competition: The case of elite archery and shooting. Eur J Sport Sci. 2021;21(11):1500-9.
Hamilton BR; Lima G; Barrett J; Seal L; Kolliari-Turner A; Wang G, et al. Correction to: Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement. Sports Med. 2021;51(7):1417-8.
MEHTA, Y., SEAL, L. J. & ANGUS-LEPPAN, H. 2021. Idiopathic Intracranial Hypertension in Transgender People: Case Report and Best Practice. J Neuroophthalmol.
Hamilton BR, Lima G, Barrett J, Seal L, Kolliari-Turner A, Wang G, Karanikolou A, Bigard X, Löllgen H, Zupet P, Ionescu A, Debruyne A, Jones N, Vonbank K, Fagnani F, Fossati C, Casasco M, Constantinou D, Wolfarth B, Niederseer D, Bosch A, Muniz-Pardos B, Casajus JA, Schneider C, Loland S, Verroken M, Marqueta PM, Arroyo F, Pedrinelli A, Natsis K, Verhagen E, Roberts WO, Lazzoli JK, Friedman R, Erdogan A, Cintron AV, Yung SP, Janse van Rensburg DC, Ramagole DA, Rozenstoka S, Drummond F, Papadopoulou T, Kumi PYO, Twycross-Lewis R, Harper J, Skiadas V, Shurlock J, Tanisawa K, Seto J, North K, Angadi SS, Martinez-Patiño MJ, Borjesson M, Di Luigi L, Dohi M, Swart J, Bilzon JLJ, Badtieva V, Zelenkova I, Steinacker JM, Bachl N, Pigozzi F, Geistlinger M, Goulis DG, Guppy F, Webborn N, Yildiz BO, Miller M, Singleton P, Pitsiladis YP. Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement. Sports Med. 2021;51(7):1401-15.
Hamilton BR, Lima G, Barrett J, Seal L, Kolliari-Turner A, Wang G, Karanikolou A, Bigard X, Löllgen H, Zupet P, Ionescu A, Debruyne A, Jones N, Vonbank K, Fagnani F, Fossati C, Casasco M, Constantinou D, Wolfarth B, Niederseer D, Bosch A, Muniz-Pardos B, Casajus JA, Schneider C, Loland S, Verroken M, Marqueta PM, Arroyo F, Pedrinelli A, Natsis K, Verhagen E, Roberts WO, Lazzoli JK, Friedman R, Erdogan A, Cintron AV, Yung SP, Janse van Rensburg DC, Ramagole DA, Rozenstoka S, Drummond F, Papadopoulou T, Kumi PYO, Twycross-Lewis R, Harper J, Skiadas V, Shurlock J, Tanisawa K, Seto J, North K, Angadi SS, Martinez-Patiño MJ, Borjesson M, Di Luigi L, Dohi M, Swart J, Bilzon JLJ, Badtieva V, Zelenkova I, Steinacker JM, Bachl N, Pigozzi F, Geistlinger M, Goulis DG, Guppy F, Webborn N, Yildiz BO, Miller M, Singleton P, Pitsiladis YP. Response to the United Nations Human Rights Council's Report on Race and Gender Discrimination in Sport: An Expression of Concern and a Call to Prioritise Research. Sports Med. 2021;51(4):839-42.
Harper J, Lima G, Kolliari-Turner A, Malinsky FR, Wang G, Martinez-Patino MJ, Angadi SS, Papadopoulou T, Pigozzi F, Seal L, Barrett J, Pitsiladis YP. The Fluidity of Gender and Implications for the Biology of Inclusion for Transgender and Intersex Athletes. Curr Sports Med Rep.2018;17(12):467-472.
Coxon J, Seal L Hormone management of trans men 2018 Trends in Urology and Men's Health Volume 9 Issue 5 Sep/Oct 2018
Coxon J, Seal L Hormone management of trans women 2018 Trends in Urology and Men's Health Volume 9 Issue 6 Nov/Dec 2018
Richards, C., Bouman, W. P., Seal, L., Barker, M. J., Nieder, T. O., & T'Sjoen, G. (2016). Non-binary or genderqueer genders. Int Rev Psychiatry, 28(1), 95-102. doi:10.3109/09540261.2015.1106446
Seal, L. J. (2015). A review of the physical and metabolic effects of cross-sex hormonal therapy in the treatment of gender dysphoria. Ann Clin Biochem. doi:10.1177/0004563215587763
Richards, C., & Seal, L. (2014a). Trans people's reproductive options and outcomes. J Fam Plann Reprod Health Care. doi:10.1136/jfprhc-2013-100669
Andrew Davies, Walter Pierre Bouman, Christina Richards, James Barrett, Sheraz Ahmad, Karen Baker, Penny Lenihan, Stuart Lorimer, Sarah Murjan, Nick Mepham, Sally Robbins-Cherry, Leighton J. Seal & Linda Stradins
Patient satisfaction with gender identity clinic services in the United Kingdom 2013 Sex and Rel Therapy 28(4) 400-18 DOI: 10.1080/14681994.2013.834321
Seal LJ Male hypogonadism and testosterone replacement therapy 2013 Medicine 41(10)557-562
Sheraz Ahmad, James Barrett, Amal Y. Beaini, Walter Pierre Bouman, Andrew Davies, Helen M. Greener, Penny Lenihan, Stuart Lorimer, Sarah Murjan,Christina Richards, Leighton J. Seal and Linda Stradins
Gender dysphoria services: a guide for general practitioners and other healthcare staff 2013 J Sex and Rel Therapy 28 (3), 172-185
L. J. Seal, S. Franklin, C. Richards, A. Shishkareva, C. Sinclaire and J. Barrett
Predictive Markers for Mammoplasty and a Comparison of Side Effect Profiles in Transwomen Taking Various Hormonal Regimens JCEM 2012 vol. 97 no. 12 4422-4428
Seal LJ Testosterone Medicine International 2009 37(9) 445-449
Shariff M, Dhillo WS, Seal LJ, Todd JF, Meeran K.
A case of excess growth hormone levels. Int J Clin Pract Suppl. 2005 Apr;(147):34-6.

Contacts:
Private Secretary – Pauline White – (07507) 054134

As Pauline does not work at either of my NHS Hospitals she therefore cannot deal with any enquires about NHS patients.

Appointments:
Cavell Private Hospital
Cavell Drive
Applicants Park Road
Enfield
EN2 7PR

Tele (020) 8366 2122

Website:
The Cavell Hospital | Private Hospital in Enfield

Clinic:
Monday 1830–2000
Last Saturday of the month 0800–1400


Nuffield health Highgate Private Hospital
17-19 View Rd
Highgate
London
N6 4DJ

Tele: 020 8341 4182

Website:
Highgate Hospital | Nuffield Health

Clinic:
Saturday 0900–1300
Except last Saturday of the month.

 
   
For appointments/correspondence to Dr Seal
please email: endoappt@protonmail.com
 
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